Early detection and multiple-sample capabilit...

Early detection and multiple-sample capability

Researchers from Los Alamos National Laboratory (LANL) and the New Mexico Consortium (NMC) received a portion of a recent $25 million grant from the US Department of Agriculture to study E. coli in the beef industry.

The USDA awarded the grant to this team of researchers to help reduce the occurrence and public health risks from Shiga toxin-producing E. coli (STEC) along the entire beef production chain.

The University of Nebraska-Lincoln are the principal investigators on the multi-institutional and multi-disciplinary team of researchers, educators and extension specialists.  The LANL-NMC portion of the grant totals $1 million for three years.

Shiga toxin-producing E. coli were a serious threat to public health and food supply, Dr. Harshini Mukundan, a LANL-NMC chemist working on the project, said.

These strains of E. coli were emerging to be a major health concern for not just the United States, but for the world at large.  The cases were  typically associated with the consumption of under-cooked beef, but raw milk and under-pasteurized apple juice could also carry the pathogen, Mukundan continued.

The goal of this research is to identify and control STEC within the beef chain and substantially mitigate the risk of STEC infections associated with beef products through cutting-edge research, outreach, and education.

Under this overall goal, Drs. Mukundan and Alina Deshpande will focus on the early detection of STEC, using novel, high-throughput technologies developed at LANL to screen beef at all levels of the production chain.  In this way, the scientists can screen multiple samples for multiple STEC markers simultaneously, rather, than the current method of one marker at a time, thereby significantly reducing the time it takes to detect, and make decisions about treating, an outbreak.
Source: Los Alamos National Laboratory